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Special attention is paid to the nosology of X-linked mental retardation.
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The findings add to the understanding of the nosology and treatment of these disorders.
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They motivate consideration of individual differences in dose-response relationships in addiction nosology and therapeutics.
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These findings have implications for treatment as well as nosology.
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RDoC intends to ground psychiatric nosology in those underlying mechanisms.
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The technique should be generally applicable to the studyofdiseases involving structural chromosomal rearrangements.
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It would be necessary only for the studyofdiseases as natural phenomena, and not for the cure of them.
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The generation of defined populations of functionally mature human GABAergic neurons represents an important step toward enabling the studyofdiseases affecting inhibitory synaptic transmission.
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A paradigm for this approach is the studyofdisorders caused by mutations in the gene for the neural cell recognition molecule L1.