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Apart from sulfonamide, very low MICs were recorded for several antibiotics tested.
2
The discovery of a new class of sulfonamide NPY Y5 receptor antagonists is described.
3
Mammals get folic acid from their diets, which means sulfonamide doesn't hobble their cells.
4
The catalytic properties and affinities for sulfonamide inhibitors and other classes of inhibitors were determined.
5
People demanded sulfonamide for every sore throat and sniffle and soon saw it as some sort of elixir.
6
Extensive SAR studies led to the discovery of sulfonamide 45 as an early lead, based on its in vitro cellular potency.
7
X-ray crystallography confirms the anticipated binding orientation and sheds light on the sulfonyl fluoride activation leading to the sulfonamide linkage to TTR.
8
A series of sulfonamide neuropeptide Y Y5 antagonists was optimized by preparation of sets of analogues using high-throughput synthesis and purification techniques.
9
There was no relationship between either the dosage or type of sulfonamide given and the time to the onset of the clinical signs.
10
The majority of patients were successfully treated with a sulfonamide-containing regimen, even though some patients had developed Nocardia infection while receiving sulfonamide prophylaxis.
11
First, it wasn't prontosil that fought off bacteria, but a derivative of it, sulfonamide, which mammal cells produce by splitting prontosil in two.
12
Nocardia infections in patients with CGD are not usually fatal if treated properly, and prophylaxis with IFN-gamma and a sulfonamide may protect against dissemination.
13
The prevalence of multi-resistant R-plasmid-bearing pathogenic and nonpathogenic bacteria in animals has increased and has been related to the use of antibiotics and sulfonamide drugs.
14
In this model the oxygen atom of the sulfonamide make hydrogen bond interactions with the catalytic residues Ser170 and Ala172.
15
We report on a field study aiming at elucidating the fate of sulfonamide (SA) antibiotics in grassland soils and their transport to surface water.
16
We have previously reported on sulfonamide and sulfone-based B1 antagonists containing a privileged bicyclic amine moiety leading to potent series of 2-oxopiperazines.