Experimental antiviral drug with potential activity against RNA viruses.
Synonyms
Examples for "favipiravir "
Examples for "favipiravir "
1 FabiFlu's price is significantly lower than versions of favipiravir in other countries, the company added.
2 The first results for brincidofovir are expected in February and for favipiravir in late March.
3 T-705 ( favipiravir ) is a new antiviral agent in advanced clinical development for influenza therapy.
4 These unique anti-viral profiles will make favipiravir a potentially promising drug for specifically untreatable RNA viral infections.
5 The antiviral favipiravir from Japan's Toyama Chemical was developed to fight RNA viruses such as the new coronavirus.
1 In contrast, T-705 acts as a potent and GTP-competitive inhibitor of the viral polymerase.
2 T-705 (favipiravir) is a new antiviral agent in advanced clinical development for influenza therapy.
3 Influenza virus-infected cell cultures were exposed to T-705 or ribavirin during single or serial virus passaging.
4 This mutagenic effect is 2-fold higher for T-705 than for ribavirin.
5 Whereas neuraminidase inhibitors slow down viral replication, T-705 is a viral RNA polymerase inhibitor which prevents viral replication.
6 These mechanisms were also proposed for ribavirin, an established and broad antiviral drug that shares structural similarity with T-705.
7 We here performed a comparative analysis of the effects of T-705 and ribavirin on influenza virus and host cell functions.
8 T-705 is also currently in phase I trials in Japan where it has been put on the Health Ministry's priority list for development.
9 Survival and virological characteristics were observed for 85 patients in the control group and 39 in the T-705 treatment group.
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