Specified amount of heat a computer component generates under normal conditions that the cooling system must dissipate.
1
However, the mechanism by which TDP-43 mutations lead to neurodegeneration is unclear.
2
Results: We identified multiple phosphorylation sites in carboxyl-terminal regions of deposited TDP-43.
3
This is consistent with new emerging ideas about TDP-43 functions in dendrites.
4
We recently identified TDP-43 as the major pathological protein in sporadic ALS.
5
Moreover, enforced repression of cryptic exons prevented cell death in TDP-43-deficient cells.