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TIFAB does not associate with members of the TRAF family but does bind TIFA.
2
RNAi was performed to knock down the endogenous expression of the TIFA gene in hepatocytes.
3
Taken together, these data suggest that TIFA is involved in the regulation of cell signaling in hypoxia-reoxygenation.
4
We recently reported that TIFA mRNA is significantly upregulated early in the liver after trauma and hemorrhagic shock.
5
Detailed analysis indicated that unphosphorylated TIFA exists as an intrinsic dimer and that the FHA-pT9 binding occurs between different dimers of TIFA.