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Results: We established a facile method to prepare sheets of decellularized term human amnion membrane and verified its nontoxicity and cell compatibility in vitro.
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A selectivity of ABCB1 inhibition is demonstrated for selected candidates and a bioanalytical study proved nontoxicity as well as missing ABCB1 substrate properties.
Usage of toxicity in English
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Future work will continue to optimize the bladder-sparing regimen while limiting toxicity.
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Consumption of any part of the plant can result in severe toxicity.
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Moderate or severe toxicity evaluated on a per course basis in …
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Purpose: Chemotherapy-induced gastrointestinal toxicity is a common adverse event during chemotherapeutic treatment.
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However, the toxicity mechanism of this species is still not fully known.
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However, its clinical potential has been limited by toxicity and water solubility.
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Objectives: Neuropsychiatric toxicity is a common dose-limiting side effect of interferon therapy.
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Radiation therapy after HDC provides excellent local control rates without excessive toxicity.
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Conclusion: Dose-attenuated CHOP does not compromise treatment efficacy but retains significant toxicity.
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However, field studies have not found evidence of toxicity at these concentrations.
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Only one combination showed significant improvement of survival, however also increased toxicity.
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Twenty-three patients received treatment and are fully evaluable for response and toxicity.
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However, MMF had less renal and hepatic toxicity and allowed weight gain.
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Hematologic toxicity was common, but did not result in cessation of therapy.
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At plasma levels higher than 200 microM there is, however, excessive toxicity.
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It is a new chemotherapy protocol with better effect and low toxicity.