1
In normal testis, c-kit expression was observed in some basal tubular cells, corresponding to undifferentiated spermatogonia.
2
However, SALL4 loss was associated with long-term functional decline of undifferentiated spermatogonia and disrupted stem cell-driven regeneration.
3
The undifferentiated spermatogonia of adult mouse testes are composed of both true stem cells and committed progenitors.
4
Sustained spermatogenesis in adult males and fertility recovery following germ cell depletion are dependent on undifferentiated spermatogonia.
5
The numbers of undifferentiated spermatogonia remained unchanged.
6
Vitamin A deficiency in the mouse results in an arrest in the progression of undifferentiated spermatogonia to differentiating spermatogonia.
7
As seen in the first experiment, the number of undifferentiated spermatogonia was significantly higher in leuprorelin-treated than in the control group.
8
We recently discovered a novel orphan G-protein coupled receptor (GPR125) that is restricted to undifferentiated spermatogonia within the testis.
9
We were able to obtain a highly enriched germ cell population with over 90% of cells being UCH-L1 positive undifferentiated spermatogonia.