There are now considerable data derived from in vivo experiments using these mice.

However, few studies using these mice have investigated the effects of mtDNA mutations on cardiovascular function.

Using these mice, we could optogenetically activate 5-HT nerve terminals and record postsynaptic effects from orexin neurons.

Using these mice, we examined the functional role of adipose ATRAP in the pathogenesis of obesity-related metabolic disorders.

Using these mice, we found that the loss of DARPP-32 in striatonigral neurons decreased basal and cocaine-induced locomotion and abolished d …