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VP7 was the only gene segment of this strain with significant genetic identity to human strains.
2
To investigate the reason why the strains were untypeable, nucleotide sequencing of the VP7 genes was performed.
3
The outer capsid proteins VP4 and VP7 are highly variable and represent the major neutralizing antigens.
4
Furthermore, a comparative analysis of the deduced amino sequences form VP7 genes of G1 rotaviruses from 12 countries indicated that four distinct lineages have evolved.
5
Thirty percent of samples in this study were mixed infections and 21 (16.7%) specimens remained untypeable either for the VP7 or for the VP4 gene.