Parkinson's is named after the English doctor JamesParkinson who published the disease's first detailed description in 1817.
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Mr O'Reilly, whio is the chief operating officer of Independent News, replaces JamesParkinson, who retired today after the company's annual meeting.
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Last year marked the 200th anniversary since JamesParkinson (1755-1824) defined the disease now named after him.
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Mr JamesParkinson (67), declined a prostate operation because he could not face four days in the Old ham Hospital without a cigarette.
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Independent's highest-paid director is head of its British operations, Mr Brendan Hopkins who received €943,000 while finance director Mr JamesParkinson received €698,000.