Significados de active metabolite en inglés

Exposure to the active metabolite SN-38 was relatively high compared with i.v.

The active metabolite was not found in plasma and urine.

Once it has entered the central nervous system, TMZ can be spontaneously converted to the active metabolite.

The neonates already possess the complete hepatic capacity for the metabolism of tramadol into its active metabolite.

A variety of biologically plausible mechanisms may mediate a hepato-protective role for the active metabolite of vitamin D3.

POR gene expression was measured by mRNA analysis and the pharmacokinetics of cyclophosphamide and its active metabolite were determined.

We conclude that losartan produces a dose-dependent, effective angiotensin II blockade that is largely determined by the active metabolite EXP3174.

The active metabolite (Ro 12-5637) could only be detected in plasma.

Tramadol is an atypical opioid with a complex mechanism of action including the synergistic interaction between the parent drug and an active metabolite.

CPT-11 is one of the most widely used Camptothecin analogues and is converted to form the active metabolite SN-38.

The concentrations of F-ara-ATP, the active metabolite of fludarabine, were determined in leukemic lymphocytes at intervals up to 24 hr after the first infusion.

The active metabolite trandolaprilat has very high lipophilicity in comparison with other ACE inhibitors, which should contribute to an improved tissue penetration of the substance.

Trandolapril is a newly developed angiotensin-converting enzyme (ACE) inhibitor that is rapidly hydrolyzed mainly in the liver to its biologically active metabolite trandolaprilat.

Retinoic acid (RA) is an active metabolite of Vitamin A, and plays an important role in the normal development of the central nervous system.

Conclusion: Beta-Est may suppress hepatic fibrosis probably via its biologically active metabolites.

After intake of heroin or morphine, active metabolites are formed in the body.