Significados de anti-fibrotic en inglés

Therefore, alternative methods are required to develop new strategies for anti-fibrotic therapy.

A small interfering RNA targeting HSP72 abolished these anti-fibrotic effects of HT.

These studies highlight the potential of inhaled GSK3008348 as an anti-fibrotic therapy.

Pirfenidone is an anti-fibrotic agent known to reduce disease progression in IPF patients.

Culture supernatants and extracted RNA were analysed for evidence of an anti-fibrotic phenotype.

New strategies for therapy of IPF followed, including anti-fibrotic agents and interferon gamma treatment.

PCS extract exerts protective effects against STZ-induced diabetic nephropathy via anti-fibrotic and anti-apoptotic effects.

Paradoxically, the degree of engraftment of human hepatocytes correlated negatively with the anti-fibrotic effect.

As well as clear anti-angiogenic effects, anti-fibrotic effects were also seen after corneal burn, maintaining corneal transparency.

Unfortunately, unless the primary disease can be eradicated there are no specific anti-fibrotic treatments in routine clinical use.

Despite efforts to develop treatment for liver fibrosis, there are no approved agents as anti-fibrotic drugs to date.

We previously demonstrated that the matricellular protein CCN5 elicits anti-fibrotic and anti-hypertrophic effects in left ventricles under pressure overload.

To confirm these results, we applied this technique to a rat UUO therapeutic model with the anti-fibrotic reagent Fasudil.

This review aims to provide an overview of the current state of CCN2 research with a focus on anti-fibrotic therapy.

To reverse this chronic disorder, anti-fibrotic therapies should target the molecular pathology of aberrant collagen accumulation in the extracellular matrix.

The aim of this study is to evaluate the safety and anti-inflammatory & anti-fibrotic activities of PBI-4050 in subjects with ALMS.