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Parallel artificialmembrane permeability assay and Caco-2 cells are the most frequently used in vitro models to assess intestinal permeability.
2
We have reconstituted intramembrane proteolysis with a pure recombinant substrate and rhomboid proteins in both detergent micelles and artificialmembrane environments.
3
Thus, the immobilized artificialmembrane provided a biophysical model system to study the passive diffusion of the statin molecules through the cellular membrane.
4
The immobilized artificialmembrane (IAM) provided a biophysical model system to study the binding of the statin molecules to a lipid membrane.
5
Nanodiscs are artificialmembrane systems comprised of discoidal lipid bilayer particles bound by annuli of amphipathic scaffold protein that shield lipid acyl chains from water.
6
Here we study the density-dependence of the diffusion of different glycosylphosphatidylinositol-anchored VSG-types on living cells and in artificialmembranes.
7
Alpha-synuclein localizes to the nerve terminal and interacts with artificialmembranes in vitro but binds weakly to native brain membranes.
8
Almost all the work to date using anti-metastatic agents has been carried out using either in vitro artificialmembranes or with animal models.