Reverse doming or fluttering was not seen in healthy volunteers or in 10 patients with congestivecardiomyopathy.
2
In patients with congestivecardiomyopathy, afterload-reduction by ACE-inhibition resulted in changes of central hemodynamics, which were closely reflected by venous concentrations of ANP.
3
Independent of nature and duration of the disease (valvular heart disease, congestivecardiomyopathy) plasma ANP levels were closely related to the severity of cardiac failure.