1
Review methods: A review of studies on adherence to CPGs was conducted.
2
Indicators were extracted from national and international CPGs and ratified by experts.
3
In particular, hypermethylation of CpG islands is a signature of malignant progression.
4
Results: Awareness and adoption of CPGs is low in thyroid cancer management.
5
Importantly, manipulating the CpG content in viral genomes could help create new vaccines.
6
Barriers to implementation include unfamiliarity with the CPGs and financial concerns.
7
The responsible gene, encoding methyl-CpG binding protein 2 was recently identified.
8
These CpG sites were further validated using an independent data set.
9
These data provide direct evidence that CpG islands regulate gene transcription of HBV.
10
We identified a local CpG sequence context associated with preferential hypomethylation in PMDs.
11
Methyl-CpG binding protein 2 is thought to act as a global transcriptional repressor.
12
Methylation-variable transitional CpGs were observed for the selected genes and the different tissues.
13
Among these genes, relative hypermethylation was observed in EC v. BE across CpGs.
14
Unmethylated CpG-ODN protect mice from infection with this fungal pathogen by inducing IFN-gamma.
15
Bioinformatic analysis revealed the presence of CpG islands in the promoter of AJAP1.
16
These associations were bidirectional, but there were pronounced negative associations for promoter CpGs.
