In conclusion, Bay 55-9837 did not show antidiabetic or antistroke efficacy in the type 2 diabeticGK rat.
2
We next treated diabeticGK rats with phlorizin for 4 weeks to determine whether restoration of glycemia would lead to improved insulin signal transduction.
3
Of the 2020 transcripts differentially regulated in diabeticGK islets when compared with controls, 1033 were up-regulated and 987 were down-regulated.