The number of corneal transplants done is far less than required due to the lack of donor cornea.

Recently we observed virus replication in a donor cornea with subsequent complete endothelial necrosis in our cornea bank.

Ex vivo gene therapy of the donor cornea has been shown to modulate graft rejection in experimental models.

Background: Gene transfer to a donor cornea ex vivo can modulate corneal graft failure in experimental animal models.

The aim of this study was to investigate the possible correlation between herpetic donor cornea infection and endothelial necrosis in organ culture.

The 105 participating surgeons at 80 sites were masked to information about the donor cornea including donor age.

The effect of ex vivo transduction of the donor cornea with LV-SV40-IL10 was assessed following orthotopic corneal transplantation in outbred sheep.

Donor cornea lenticules were prepared and a wet lab DSAEK model established.

Thirty donor corneas and 10 patients undergoing DSAEK with glide insertion were included.

Purpose: Donor corneas are processed in eye banks and used for transplantation as a standard routine.

Twenty-seven donor corneas were analyzed.

One month postoperatively, there was no improvement in the vision, and both patients had pronounced swelling of the recipient and donor corneas.

Each approach represents a unique strategy toward the same goal: to develop a new hydrogel that mimics the important properties of natural donor corneas.

The percentage of hexagonal cells and figure coefficient for the donor corneas were 60.5% and 0.8774, respectively.

Eight pairs of human donor corneas underwent calcein acetoxymethyl staining-all right eyes underwent the peeling technique and all left eyes underwent the lamellar dissection technique.

For the study, the researchers recruited 1,090 people ranging in age from 40 to 80 years old to receive donor corneas.