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DPCs can be induced endogenously or through environmentalcarcinogens and chemotherapeutic agents.
2
Genetic alterations in cancer tissues may reflect the mutational fingerprint of environmentalcarcinogens.
3
Asbestos, like many environmentalcarcinogens, has a long latency period.
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These techniques are particularly useful for screening human populations for exposure to potential environmentalcarcinogens.
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Results demonstrate that cumulative exposures to multiple environmentalcarcinogens and neurotoxins can be comparatively high for children from a poor inner-city neighborhood.
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Conclusions: These results point toward a role of AGT polymorphisms in lung cancer susceptibility among never-smokers, in particular among subjects exposed to environmentalcarcinogens.
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Current knowledge is insufficient to explain why only a proportion of individuals exposed to environmentalcarcinogens or carrying a genetic predisposition to cancer develop disease.
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Environmentalcarcinogens, in a strict sense, include outdoor and indoor air pollutants, as well as soil and drinking water contaminants.