Significados de fibulin en inglés

However, the effect of tumor-derived versus host microenvironment-derived fibulin-5 remains to be evaluated.

Baseline plasma fibulin-1 correlated with BP and estimated glomerular filtration rate.

For larger cohorts TRIFMA provides a faster platform for fibulin-1 quantitation in plasma.

This study aimed to evaluate whether antihypertensive treatment with spironolactone changes plasma fibulin-1 levels.

Moreover, fibulin-1 circulates in high concentrations in plasma and may function as a cardiovascular disease marker.

Purpose: The expression of fibulin-5 was investigated in urothelial carcinomas of bladder and in normal bladder samples.

In contrast, up-regulated keratin 19 and fibulin-1 were confined to cystic epithelia.

These results also support the potential use of fibulin-5 as a therapeutic agent for the treatment of elastinopathies.

Solid-phase binding assays indicated normal molecular interaction of Delta16-17 with fibrillin-1 and fibulin-5.

Conclusions: Our data collectively suggest fibulin-1C may be worthy of further investigation as a target for airway remodeling in asthma.

However, aneurysms are never seen in mice deficient for elastin, or for fibulin-5, which absence also leads to compromised elastic fibers.

The function of fibulin-1C was determined by assessing its role, using an antisense oligonucleotide, in cell proliferation, migration and wound healing.

Further studies on the role of fibulin-1 in the regulation of eye growth, including during the development of myopia, are therefore warranted.

Treatment with low-dose spironolactone reduced plasma fibulin-1 levels in patients with type 2 diabetes and resistant hypertension.

Furthermore, fibulin-4 deficiency caused enhanced susceptibility of bone collagen for acid extraction, consistent with significantly reduced lysylpyridinoline and hydroxylysylpyridinoline cross-links in bone.

Blood pressure (BP) and plasma fibulin-1 were measured at baseline and at 16 weeks follow-up.