This is the first report of a continuous process for biocatalytic formate production.

WI 14 is able to catalyse the oxidation of methanol to formate directly.

We found that maternal formate supplementation largely corrects these disruptions in Mthfd1l-null embryos.

However, mitochondria isolated from AS23 tubers could not use formate as a respiratory substrate.

The leaf-like structure effects a bias-free biocatalytic CO 2 -to-formate conversion under visible light.