Significados de genomic rearrangement en inglés

Encoded in the views are large-scale genomic rearrangement events and functional landmarks.

Here, we present the package Cassis that implements this method of precise detection of genomic rearrangement breakpoints.

The Streptomyces glaucescens genome frequently undergoes gross genomic rearrangement events which result in the deletion of extremely large segments of chromosomal DNA.

Identification of patients sharing a genomic rearrangement and having phenotypes in common increases certainty in the diagnosis and allows characterization of new syndromes.

The presence of the same TcR genomic rearrangement suggests the origin from a common progenitor able to differentiate along both T- and NK-pathways.

Principal findings: Substantial genomic rearrangement and heterogeneity were observed that appeared to have resulted from both mobile elements and substantial lateral gene transfer.

Recombination between them can lead to genomic rearrangements of clinical and evolutionary significance.

Presence of genomic rearrangements was assessed by multiplex ligation-dependent probe amplification.

Screening for genomic rearrangements appears indicated in patients suspected of defective DNA damage responses.

However, computing sensitive and accurate genome alignments is a challenging problem, complicated by genomic rearrangements.

Objective: To estimate the contribution of large genomic rearrangements to the spectrum of BRCA2 defects.

No genomic rearrangements or mutations in TGFb3 were identified.

This case suggest that a defective ATM-dependent DNA damage response may entail additional stochastic genomic rearrangements.

The exon 13 duplication was detected in one family, and four families had other genomic rearrangements.

Despite the ubiquity of genomic rearrangements, the forces that underlie their genesis are not well understood.

The breakpoints of the genomic rearrangements were assessed by a long-range polymerase chain reaction and sequencing.