The new metabolites fall into two categories, glucuronides and phenylbutyrate beta-oxidation side products.
2
Plasma concentrations of morphine and its glucuronides were not significantly changed by quinidine pretreatment.
3
The method was applied in profiling of targeted and nontargeted steroids and steroid glucuronides during pregnancy.
4
The results suggest that steroids and especially steroid glucuronides may provide a valuable diagnostic tool to follow the course of pregnancy.
5
The method provides high sensitivity and fast analysis, as both steroids and their glucuronides can be analyzed directly without hydrolysis or complex sample preparation.
Uso de glucuronide en inglés
1
Yet, it had a different selectivity profile than either morphine or morphine-6beta-glucuronide.
2
Morphine-6beta-glucuronide is a major metabolite of morphine with potent analgesic actions.
3
Results: Numbers of THC-glucuronide and CBD-positive blood samples were insufficient to assess stability.
4
Plasma concentrations of an inactive ciclopirox glucuronide metabolite were greater than those of ciclopirox.
5
This suggests that morphine-glucuronide metabolites may play a role in the development of addiction to morphine.
6
Codeine-6-glucuronide is the most likely additional active moiety.
7
Biotransformation of the methyl derivatives of UDCA occurred mainly by conversion to more polar glucuronide conjugates.
8
Plasma concentrations of morphine and its glucuronide metabolites were measured throughout the observation period of 5 hours.
9
Catechin was present as both a sulfate conjugate and a conjugate containing both glucuronide and sulfate residues.
10
Lamotrigine and the 2-N-glucuronide were typically detected, while the N-methyl and N-oxide metabolites were detected only rarely.
11
Recent studies demonstrated that orally administered quercetin appeared in plasma as glucuronide-conjugated forms in rats and humans.
12
The major metabolites of BG in rat urine and plasma proved to be BG-O-glucuronide and O-methyl BG-O-glucuronide.
13
The reliability of ethyl glucuronide and other biomarkers for the detection of alcohol abuse is being better established.
14
These findings suggest a predominantly urinary excretion route of bisphenol A glucuronide in chimeric mice with humanized liver.
15
A small portion of the metabolite was excreted into urine as balofloxacin glucuronide and N-desmethyl balofloxacin in these species.
16
Significant conversion of 502U83 to two glucuronide metabolites was detected.