Significados de hepatic stellate en inglés

Background: Human hepatic stellate cells have been shown to be resistant to apoptotic stimuli.

SSeCKS protein expression was mainly found in hepatic stellate cells.

The alpha-smooth muscle actin is a well known marker of hepatic stellate cells activation.

CCL16 might impact liver cirrhosis through inactivating hepatic stellate cells.

The major part of pPB-HSA in the fibrotic liver was localized in hepatic stellate cells.

Long-term treatment with rifampicin over several weeks reduced the proliferation and transdifferentiation of hepatic stellate cells.

The results revealed that ADAMTS13 was expressed primarily in cell fractions enriched in hepatic stellate cells.

In this study we explored the effects of myostatin on the biology of hepatic stellate cells.

These compounds blocked activation of phosphatidylinositol 3-kinase and inhibited insulin-like growth factor-I-induced hepatic stellate cells migration.

The combination of nicotine and ethanol also activated hepatic stellate cells, a principal liver fibrogenic cell.

These findings were associated with significant reductions in liver fibrosis, hepatic stellate cell activation, and desmin expression.

In chronic hepatitis livers and in the cirrhotic ones, hepatic stellate cells became larger with long cytoplasmic processes.

Conclusion: In addition to Bcl-2, several other anti-apoptotic pathways are responsible for human hepatic stellate cell resistance to apoptosis.

TR expression was also shown in cultured human hepatic stellate cells, with increasing signal comparing activated versus quiescent cells.

The role of insulin growth factor-I as a survival factor in human hepatic stellate cells needs to be substantiated.

Conclusions: SHH expression in the liver induces liver fibrosis with concurrent activation of hepatic stellate cells and fibrogenic genes.