Radical C-H bond functionalization provides a versatile approach for elaborating heterocyclic compounds.
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Meat Barbecuing is known to generate potentially cancer-causing chemicals known as heterocyclic amines.
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Commercial application of many promising heterocyclic natural products is limited by their natural abundance.
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The method provides facile access to a wide range of previously unknown heterocyclic structures.
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This study only provides weak support for a similar association with meat heterocyclic amines.
1
Radical C-H bond functionalization provides a versatile approach for elaborating heterocycliccompounds.
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In addition, the protocol can be further applied in the synthesis of heterocycliccompounds like benzimidazoles.
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The substrates are mostly heterocycliccompounds.
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As part of our continuing studies of polymer-supported pericyclic reactions for preparing biologically interesting heterocycliccompounds, we have introduced a traceless solid-phase synthesis of hexahydrocinnolines.
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Isovanillin has been shown to inhibit the metabolism of aromatic aldehydes by aldehyde oxidase, but its inhibition towards the heterocycliccompounds has not been studied.
Uso de heterocycle en inglés
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AHFC promoted the decomposition of protein to form heterocycle compounds in the resulting cake according to in situ FTIR results.
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A series of pleuromutilins modified by introduction of a boron-containing heterocycle on C(14) of the polycyclic core are described.
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Structure-activity studies demonstrate the requirement for the core heterocycle in addition to an optimal 2,6-disubstituted aniline group.
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Previous works in our laboratories established the bioisosteric equivalency of the indole heterocycle and naphthalene in a series of melatonin receptor ligands.
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The possible reaction pathway of N-heterocycle compounds formation from cellulose during hydrothermal liquefaction with NH 3 ·H 2 O was proposed.
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The reactivity, synthesis, and structure of the mesoionic 3-substituted-1,2,3,4-oxatriazole derivatives described here provide interesting new information on this known but poorly understood heterocycle.
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Their activity has been related to the nature of the added heterocycles.
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This is the first report on the hydrothermal generation of two fused heterocycles.
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Further manipulation of the dihydropyrimidone skeleton gives access to unique heterocycles.
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A number of interesting points regarding the chemistry of medium-ring oxygen heterocycles are highlighted.
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This enables rapid and reliable regioselectivity prediction for radical C-H bond functionalization of heterocycles.
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Vinyl azides are highly versatile synthons that provide access to numerous N-heterocycles and other functional groups.
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Results: Shape and electrostatic similarity matching was used to select five-membered heterocycles to replace the ethyl ester functionality.
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The heterocycles and their mixture displayed efficient solvent dependent fluorescence in the visible region of the solar spectrum.
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These results suggest that thiadiazole urea heterocycles which incorporate a substituted phenylalanine can provide selective inhibitors of stromelysin.
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The enzymes aldehyde oxidase and xanthine oxidase catalyze the oxidation of a wide range of N-heterocycles and aldehydes.