Compound 8 exhibited highpotency against BTK kinase and acceptable PK profile.
2
The vectors showed highpotency for in vitro and in vivo transduction.
3
The activation of these additional TFs by glycosylated IFN-omega might contribute to its highpotency.
4
Among the resulting compounds, many showed highpotency and improved physicochemical properties in comparison with the lead.
5
The series of compounds can afford highpotency on MC4R as well as good rodent pharmacokinetic profiles.
6
The main contaminant contained in the emissions was arsenic, which is classified as a non-threshold, highpotency carcinogen.
7
Symmetrical para substituents of the benzene rings are important for highpotency in binding to the dopamine transporter.
8
The combined modifications of the A-ring at the 2-position and the side chain yielded analogues with highpotency.
9
They had Sam Browne belts of highpotency, and we had no substitute even for that insignia of power.
10
Avoidance of precipitating factors, optimal skin care, and high or ultra- highpotency topical corticosteroids are the mainstay of therapy.
11
Given the highpotency of 20:4, n-6, its effect on adipocyte gene expression was characterized.
12
The harm caused by synthetic cannabinoids could be related to the extremely highpotency of the drugs, Prof Glass said.
13
Volatile sulphur compounds (VSCs) are important to the food industry due to their highpotency and presence in many foods.
14
The study found the link between cannabis and psychosis was strongest in London and Amsterdam, where highpotency skunk is commonly available.
15
Reversal of the 6-oxymethylene linkage also permitted highpotency and improved stability towards human liver microsomes, albeit, in vivo results were inferior.
16
Synthesized compounds were evaluated for their alkaline phosphatases inhibition potential and exhibited highpotency as well as selectivity towards h-TNAP and h-IAP.