1
Appropriate immune responses require a fine balance between immune activation and attenuation.
2
Patients with metastases exhibiting MSI-independent immune activation experience the most favorable survival.
3
The mechanisms causing these varying levels of immune activation are not understood.
4
Plasma markers of innate immune activation were measured using standard ELISA-based assays.
5
HIV-1 enteropathy is associated with increased microbial translocation and systemic immune activation.
6
However, little is known about the molecular requirements resulting in successful immune activation.
7
However, suppression of immune activation also limits viral clearance and promotes reservoir formation.
8
Furthermore, simultaneous stimulation of several Toll-like receptors may mimic general innate immune activation.
9
However, the relationship between viremia and systemic immune activation is unclear.
10
This event likely occurs before systemic immune activation reaches peak levels.
11
In contrast, immune activation was prevented by tacrolimus with significantly improved recipient survival.
12
Functional enrichment analysis revealed that CD3D is related to immune activation and regulation.
13
High pre-ART levels of each biomarker strongly predicted residual immune activation during ART.
14
Initiation of antiretroviral therapy during acute HIV-1 infection may prevent persistent immune activation.
15
Chronic HIV infection is characterized by increased immune activation and immunosenescence.
16
How immune activation differs among HIV-infected and HIV-uninfected adults with pneumonia is unknown.
