Changes in the threshold for Hebbian plasticity were evaluated by inducingLTP with stimulation protocols of increasing strength.
2
The high-frequency stimuli used to induceLTP produced an extracellular negativity at the bicuculline electrode that was not present at the control electrode.
3
We then recorded E-S curves from 9 such electrodes and from 8 control electrodes before and after inducingLTP in the perforant path.