The instauration of general anaesthesia came from experiments made on man alone.

It is fortunate for me that I have been an eye-witness of the progress made in this department from its practical instauration.

However, before instauration of these treatments, the risk of immune reconstitution inflammatory syndrome and potential exacerbation of an underlying disease must be considered.

The Missing Books of the Great Instauration or 'Philosophy itself'

Lord Bacon outlined his gigantic plan for "the Instauration of the Sciences" during the four years spent in the University of Cambridge.