Significados de leukocyte trafficking en inglés

The innate mechanisms driving (or inhibiting) leukocyte trafficking to allografts remain incompletely understood.

We now show that aldosterone triggers endothelial cell exocytosis, the first step in leukocyte trafficking.

Our data show that antibody to host antigens can activate human endothelial cell exocytosis and leukocyte trafficking.

We hypothesized that endothelial expression of such guidance cues may regulate leukocyte trafficking into the vascular wall during atherogenesis.

Uveitis was assessed using intravital videomicroscopy, which visualizes leukocyte trafficking within the vasculature and tissue of the iris, and by histology.

In vivo microscopy of leukocyte trafficking was performed in non-thrombosed mice, and tissue and plasma were harvested during early VT formation.

These data indicate a previously unappreciated role for axonal guidance cues in maintaining the endothelial barrier and regulating leukocyte trafficking during atherogenesis.

Importantly, in healthy neonates, blocking TNF-a at birth disrupted the physiologic leukocyte trafficking, which resulted in persistently altered leukocyte profiles at barrier sites.

First thought to orchestrate exclusively leukocyte trafficking, chemokines are now acknowledged for their multiple roles in the regulation of cell proliferation, differentiation, and survival.

The drug's activity is based on an improved permeabilization of newly formed tumor vasculature, which favors intratumor penetration of chemotherapeutic agents and leukocyte trafficking.

Leukocyte trafficking and recruitment is a critical process in host immune surveillance and in inflammatory diseases.

Leukocyte trafficking into the CNS is a prominent feature driving the immunopathogenesis of multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis.