First, different ligands for a given TAAR can vary in behavioral effect.
2
However, the unique and overlapping roles of these ligands remain poorly understood.
3
However the development of peptides as pharmaceutical ligands has been more limited.
4
Therefore, we examined primary stromal cell cultures for expression of Notch ligands.
5
Soluble ligands are important targets for therapy of cancers and other diseases.
1
All experimental evidences suggest that the presence of zirconium can minimise the polymerisation of hafnium, favouring its reaction with the studied complexingagent.
2
The results provide insights into the role of complexingagents and guide the future design of zinc-bromine flow batteries.
3
Zinc-bromine flow batteries are promising for stationary energy storage, and bromine- complexingagents have been used to form phase-separated liquid polybromide products.
4
This methodology is dramatically different from other CE methods that have used complexingagents such as micelles or cyclodextrins in MEKC.
5
Both morphologies and phases of the CdSe products could be successfully controlled by choosing appropriate complexingagents to adjust the dynamics of the reaction process.
Uso de ligand en inglés
1
However, information on ligand and target gene-specific requirements for coactivators is limited.
2
This region, therefore, is likely to constitute a site for ligand-receptor interaction.
3
The latter effect was associated with increased T cell CD40 ligand expression.
4
It is predicted that all START domains contain a similar ligand-binding pocket.
5
Sequences were identified that modulate galectin binding to its natural carbohydrate ligand.
6
Reproducible structural information and detailed validation of protein-ligand interactions aid drug discovery.
7
Molecular design incorporating macrocycles may lead to molecules with unique protein-ligand interactions.
8
A unique loop lining the shallow groove suggests a different ligand-binding mechanism.
9
This is consistent with stabilisation of the protein structure by ligand binding.
10
An affinity adsorbent for PD was prepared using beta-primeverosylamidine as a ligand.
11
Cell-cell communication via ligand-receptor signaling is a fundamental feature of complex organs.
12
These methodological improvements should be useful for many applications of protein-ligand design.
13
Each ligand, in turn, is likely to activate more than one receptor.
14
The role of TNF and Fas-ligand in hepatocyte mitosis also was assessed.
15
We also investigated the contribution of ligand degradation to the Nodal gradient.
16
This Notch ligand then induces neighboring cells to become nonneuronal cone cells.