The T cell co-receptor PD-1 is selectively incorporated into ectosomes.
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In some instances, extracellularmicrovesicles harboring infectious virus have been found.
Uso de microvesicles en inglés
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The numerical density of Golgi-associated microvesicles per Golgi volume unit also increased.
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The tissue factor is present on microvesicles originated from activated leukocytes.
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In some instances, extracellular microvesicles harboring infectious virus have been found.
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Various cell-specific markers were used to identify the cellular source of TF+ microvesicles.
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Leukocytes generate tissue factor containing microvesicles following stimulation with cytokines and following platelet adhesion via P-selectin.
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Circulating RNA molecules are resistant to degradation by RNases because they are encapsulated in membrane-bound microvesicles.
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Conclusions: This study is the first to identify and define miRNA expression in circulating plasma microvesicles of normal subjects.
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Here, we report that GHCer becomes incorporated into endothelial cells through the absorption of microvesicles shed from tumor cells.
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An emerging approach for cancer treatment employs the use of extracellular vesicles, specifically exosomes and microvesicles, as delivery vehicles.
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RNA was isolated from both the microvesicles and matched mononuclear cells and profiled for 420 known mature miRNAs by real-time PCR.
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In addition to peptide-containing large dense-core vesicles, axon terminals from these cells contain clear microvesicles that have been shown to contain glutamate.
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Sucrose density gradient fractionation and vesicle immunoisolation experiments suggest that Syt IV protein is present in both synaptic-like microvesicles and secretory granules.
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Increased proliferation and activation of cells, determined by the observations of microvesicles shedding processes, provided evidence of the availability of the drug.
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Extracellular vesicles, such as exosomes and microvesicles, are released from tumor cells and can transfer biologically active proteins and RNA across cells.
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In this study, we demonstrate that various types of macrophages internalize microvesicles, called exosomes, secreted by breast cancer and non-cancerous cell lines.
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Moreover, the analysis of the distribution and localization of cellular microvesicles was performed to evaluate the influence of functionalized surfaces on cellular cytophysiological activity.