Significados de naïve t en inglés

Prominent immune alterations associated with aging include the loss of naïve T-cell numbers, diversity and function.

The naïve T-cell pool and thymic production of naive cells are key determinants of children's CD4 levels.

Epidermal Langerhans cells represent an immature population of dendritic cells, not yet able to prime naïve T cells.

Therefore, latent MCMV infection resulted in pronounced changes of the T-cell compartment consistent with impaired naïve T-cell function.

We tested the ability of our lead construct to redirect naïve T cells and induce target cell-specific lysis.

Objective: Interleukin-12 is essential for the differentiation of naïve T cells into interferon-γ-producing T cells, which regulate inflammatory responses.

The molecular events leading to the activation of naïve T cells have been extensively studied and are well characterized.

One puzzle is that the potential repertoire greatly exceeds the realized diversity of naïve T cells within any individual.

All the cell types used efficiently induced statistically significant naïve T cell proliferation at all culture time points and responder:stimulator ratios used.

Relatively quiescent naïve T cells only require energy for survival and migration, and they mainly metabolize glucose to carbon dioxide through oxidative phosphorylation.

RAPA plus TGF-β induces human naïve T cells to become suppressor cells, a novel strategy for treating human autoimmune diseases and preventing allograft rejection.

Dendritic cells (DC) interact with naïve T cells to regulate the delicate balance between immunity and tolerance required to maintain immunological homeostasis.

Genital infection with C. muridarum also stimulated high levels of costimulatory molecules on cDC central for the activation of naïve T cells in vivo.

Memory immune responses are mediated by antigen-specific memory T lymphocytes that exhibit enhanced function compared with naïve T cells that have never encountered antigen.

Incubation of ethylenecarbodiimide-coupled antigen presenting cells (APC) with naïve T cells and antigen has been shown to induce tolerance in various experimental models.

In contrast, the CD8 T cell compartment is more unstable, with progressive diminution of naïve T cells and increasing loss of diversity during mid adulthood.