Pots is a disorder where orthostaticintolerance (OI) is the main symptom.
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Whether myocardial contractile impairment contributes to orthostaticintolerance (OI) is controversial.
3
Postural tachycardia syndrome (POTS) is a form of dysautonomia which presents with complex symptoms including orthostaticintolerance.
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Diagnosis of POTS was based on chronic day-to-day orthostaticintolerance symptoms as well as excessive tachycardia during the TTT.
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Recent studies have suggested that microgravity-induced arterial remodelling contributes to post-flight orthostaticintolerance and that multiple mechanisms are involved in arterial remodelling.
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This study validates NA signalling impairment as a widespread process in microgravity, which may most dramatically result in the clinical phenotype of orthostaticintolerance.
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Alterations in autonomic function were reported in 97.1% of the cases, with statistical significance in orthostaticintolerance and gastrointestinal domain scores.
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Orthostaticintolerance is when a significantly reduced volume of blood returns to the heart after a person stands up from a lying-down position.