No decomposition or other reactions of 1 by free phosphonic acid moieties occur.

The phosphonic acid ligands have been synthesized from their corresponding bromides following two different types of reactions.

The reaction of pyridyl-4- phosphonic acid with three different divalent metal salts results in the formation of molecular structures of different dimensionality.

Phosphonic acid derivatives provide a basis for stable chemical binding on metal oxide surfaces.

In bacterial growth inhibition assays, the phosphonic acids generally resulted in poor antibacterial activity, likely a reflection of inadequate permeability.