Significados de polyketides en inglés

A synthesis of the ABC-rings of the polyketide natural product hexacyclinic acid has been achieved.

The two essential structural components of macrolide antibiotics are the polyketide aglycone and the appended sugars.

Feeding experiments using (13)C-labeled acetate were carried out to confirm that the angucycline core is indeed polyketide-derived.

The present study confirmed the presence of the unusual pathway in the biosynthesis of a hybrid peptide-polyketide natural product.

This result clearly indicated that macrolactone formation proceeds 15-OH oxidation since the linear polyketide is not a substrate for SpnJ.