Significados de postmortem brain en inglés

Many gene expression studies have examined postmortem brain tissues of patients with schizophrenia.

In postmortem brain tissue available from one patient, histology and immunohistochemistry were performed.

Gene expression profiles of postmortem brain tissue represent important resources for understanding neuropsychiatric illnesses.

The subtypes are also differentially altered in postmortem brain samples from Alzheimer disease cases.

Evidence from postmortem brain studies have indicated that early prenatal development may be altered in autism.

Aberrant GluRdelta2 glutamate receptor localization and dendritic spine morphology were observed in the postmortem brain specimen.

Here, we describe the successful application and optimisation of 2-D DIGE technology for human postmortem brain studies.

We used calcium phosphate precipitation to analyze an AD postmortem brain, followed by liquid chromatography-tandem mass spectrometry.

Recent postmortem brain and imaging studies provide evidence for disturbances of structural and synaptic plasticity in patients with mood disorders.

Our results demonstrate that PSD fractions can be isolated from human postmortem brain tissues with a reasonable degree of integrity.

This approach may foster novel postmortem brain research paradigms in which the stoichiometry and protein composition of specific microdomains are examined.

We review the literature derived from animal models of these disorders as well as from studies of postmortem brain tissue from human patients.

Background: Suicidality and impulsive aggression are partially heritable, and postmortem brain studies suggest that abnormalities in serotonin 1B may be associated with suicide.

Although postmortem brain studies have indicated altered expression levels of NCAM and L1, it is still unclear whether these changes are state- or trait-dependent.

Results: A subset of autism-iPSC cortical neurons were RNA-sequenced to reveal autism-specific signatures similar to postmortem brain studies, indicating a potential common biological mechanism.

The interpretation of postmortem brain studies involving broad mitochondrial gene expression and related pathway alterations must be monitored against the strong effect of agonal-pH state.