Significados de posttranslational modification en inglés

Mono-ADP-ribosylation is a reversible posttranslational modification that modulates the function of target proteins.

A total of 14 proteins had changes suggesting altered posttranslational modification.

Here, we describe a previously unknown posttranslational modification of the DNA-binding domain of p53.

Protein methylation is a common posttranslational modification that mostly occurs on arginine and lysine residues.

This enzyme catalyzes O-GlcNAcylation, a posttranslational modification that is influenced by the cellular metabolic state.

Prenylation is a posttranslational modification essential for the proper localization and function of many proteins.

Acetylation of lysine residues is an important posttranslational modification found in all domains of life.

Protein phosphorylation is a ubiquitous posttranslational modification that regulates cell signaling in both prokaryotes and eukaryotes.

S-Nitrosation is a key posttranslational modification in regulating proteins in both normal physiology and diverse human diseases.

Phosphorylation of proteins is a key posttranslational modification in cellular signaling, regulating many aspects of cellular responses.

Protein phosphorylation represents the most dominant and evolutionary conserved posttranslational modification for information transfer in cells and organisms.

The Golgi apparatus plays an indispensable role in posttranslational modification and transport of proteins to their target destinations.

An emergent mechanism for regulating synapse function is posttranslational modification through the ubiquitin pathway at the postsynaptic membrane.

The repair of DSBs involves both posttranslational modification of nucleosomes and concentration of DNA-repair proteins at the site of damage.

Although posttranslational modification of clock proteins is likely to finely control their circadian functions, only limited information is available to date.

There is, however, growing evidence that posttranslational modification of histones is a dynamic process that shows many correlations with gene expression.