Significados de productive elongation en inglés

Elongation complexes of the second class carry out productive elongation in which long transcripts can be synthesized.

The P-TEFb-dependent transition into productive elongation was also inhibited by THZ1, likely due to loss of DSIF.

The ability to carry out productive elongation can be restored to isolated transcription complexes by the addition of P-TEF after initiation.

In unicellular organisms, initiation is the rate-limiting step in transcription; in metazoan organisms, the transition from initiation to productive elongation is also important.

Transcriptional regulation in eukaryotes occurs at promoter-proximal regions wherein transcriptionally engaged RNA polymerase II (Pol II) pauses before proceeding toward productive elongation.

Most human genes are loaded with promoter-proximally paused RNA polymerase II (Pol II) molecules that are poised for release into productive elongation by P-TEFb.

Productive elongation complexes are derived from early paused elongation complexes by the action of a factor which we call P-TEF (positive transcription elongation factor).