This truncated polypeptide contains the N-terminus of PS1 and appeared unchanged across cases.
2
PS1 null mice are embryonic lethal and exhibit axial skeleton malformation and CNS defects.
3
A highly specific monoclonal antibody was developed to identify and characterize the native PS1 protein.
4
Therefore, re-examination and detailed analyses are needed to clarify the relationship between PS1 function and UPR signaling.
5
Royal Ontario Museum Return on Marketing Read-only message Read-only memory When did Sony release the PS1 console?
6
PS1 immunoreactivity was present in the neuritic component of senile plaques as well as in neurofibrillary tangles.
7
Taken together, these findings suggest that PS1 participates physically in a complex with APP during the gamma-secretase cleavage event.
8
However, the ER localization of PS1 is inconsistent with that hypothesis, since Notch cleavage occurs near the cell surface.
9
These effects were not related to altered γ-secretase activity or PS1 binding to TV3.
10
"I'm sorry to tell you, Alice, you're positive for the PS1 mutation."
11
In the olfactory bulb, PS1 mRNA was strongly expressed in both olfactory bulb neuroepithelium and the differentiating olfactory bulb.
12
You can download from the Net, it plays everything designed for PS1, it plays DVD sex movies, DVD games.
13
I got very excited this summer about Ryan Trecartin who's a video artist, had a big show at PS1.
14
The vast majority of individuals affected with early onset familial Alzheimer's disease (FAD) carry missense mutations in PS1.
15
In addition, PS1 and its orthologues facilitate signaling of Notch family members, cell-surface receptors that specify cell fates during development.
16
These findings raise the intriguing possibility that PS1-beta-catenin interactions and subsequent activities may be consequential for the pathogenesis of AD.