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It is typically characterized by congenital microcephaly, intractable seizures of infantile onset, and severe psychomotorretardation.
2
The poor test performance was mainly associated with psychomotorretardation and decreased concentration in depressed individuals.
3
The psychomotorretardation is thought to be caused by impaired neuronal T3 uptake during brain development.
4
In addition, data have indicated significantly improved psychomotorretardation in patients with depression after 3 months of treatment.
5
Clinically, half of the patients presented with severe AIDS dementia complex including advanced psychomotorretardation and behavioural dysfunction.
6
In the patient group, cumulative depression duration was not significantly correlated with cognitive function, apathy, anhedonia or psychomotorretardation.
7
The principal clinical symptoms that may be a clue to cerebral malformation include congenital hemiparesis, epilepsy and mental or psychomotorretardation.
8
CD results in spongiform degeneration of the brain and severe psychomotorretardation, and the affected children usually die by the age of 10.
9
Neuropsychological tests and scales for apathy, anhedonia and psychomotorretardation were assessed in 23 female patients and 60 healthy age-matched female controls.
10
Psychomotorretardation is a prominent symptom during the 6 weeks of assessment, and its severity at baseline is negatively associated with clinical remission.