It is therefore crucial to limit thymine-replacing uracils.dUTP is constantly produced in the pyrimidinebiosynthesis network.
2
Adipocyte Xbp1s overexpression drives energy mobilization and protects mice from obesity through activation of the pyrimidinebiosynthesis pathway.
3
Next to the inhibition of pyrimidinebiosynthesis and proliferation of activated lymphocytes, it seems to have multiple anti-inflammatory and immunomodulating effects.
4
A putative uracil phosphoribosyltransferase gene was found upstream of the barbiturase gene, suggesting mutual interaction between pyrimidinebiosynthesis and oxidative degradation.
5
This transcriptional rigidity carried over to metabolically related RNA encoding folate and pyrimidinebiosynthesis, as well as to the rest of the parasite genome.