Significados de senescent mice en inglés

In this study we investigated the mechanism of dominant arrhythmia vulnerability of RV in senescent mice.

This study tests the hypothesis that cardiac function is uniquely altered by PM exposure in senescent mice.

This deficit contrasts with the maintenance of the normal number of total peripheral B lymphocytes in senescent mice.

Therefore, we have focused on the regulation of E2A expression and function during both B lymphopoiesis and isotype class switching in senescent mice.

Objective: This study sought to assess the mechanism of dominant RV arrhythmia vulnerability in senescent mice as a model of general reduced myocardial integrity.

However, in senescent mice, heterogeneously distributed patches of replacement fibrosis were present throughout the entire RV myocardium, but only in midendocardium and subendocardium of LV.

Thus, myostatin deletion does not affect aging-related increases in cardiac mass and appears beneficial for bone density, insulin sensitivity and heart function in senescent mice.

Senescent mice revealed decreased conduction velocity, increased aniso-tropic ratio and reduced excitation wavelength in RV, but not in LV.