We have no meanings for "severe ra" in our records yet.
1 Conclusions: In Brazil, moderate to severe RA is associated with significant functional disability and morbidity.
2 More aggressive treatment strategies may be needed to effectively manage patients with moderate to severe RA .
3 Hospitalisation rate and frequency of physician consultations were also significantly greater among those with severe RA .
4 The clinical parameters of disease activity were similar in each treatment group and were consistent with active and severe RA .
5 IgA RF has been associated with severe RA and may thus be indirectly correlated with a genotype encoding low IL-10 production.
6 Conclusion: This study confirmed both the efficacy and the safety of IL-1Ra in a large cohort of patients with active and severe RA .
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