Here, we report the development of a panel of human GPIHBP1- specificmAbs.
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Directional transport of specificmRNAs is of primary biological relevance.
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Depleting LT-alpha- specificmAb inhibited T cell-mediated models of delayed-type hypersensitivity and experimental autoimmune encephalomyelitis.
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This apparently coordinated accumulation of specificmRNAs results from increased transcription of the relevant genes.
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How these RNA structures mediate eIF3 recruitment to affect translation of specificmRNAs remains unclear.
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Serial Southern hybridization in this study confirmed the specificmRNA expression corresponding to each enzyme.
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As expected, specificmRNA levels correlated with the intensity of lacZ expression for each variant.
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They bind to the 3'-untranslated region of specificmRNAs and inhibit translation or promote mRNA degradation.
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Freshly isolated lymphocytes were analyzed by flow cytometry using a panel of V gene subset- specificmAbs.
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The same method could also be applied to other RNA-binding proteins interacting with specificmRNAs or miRNAs.
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Two alternative promoters underlie the transcription of two classes of HOX-5.1- specificmRNAs.
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MicroRNAs are small noncoding RNAs that regulate gene expression by targeting specificmRNAs for degradation or translation inhibition.
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Accumulating evidence suggests that changes of the protein synthesis machinery alter translation of specificmRNAs and participate in malignant transformation.
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Tryptophan-activated TRAP negatively regulates expression by binding to specificmRNA sequences and either promoting transcription termination or blocking translation initiation.
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The examination of YY1- specificmRNA expression demonstrated at least six mRNA isoforms ubiquitously expressed in normal human adult and fetal tissues.
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One stable clone decreased the efflux of rapidly labeled RNA and of one specificmRNA (ovalbumin) from isolated nuclei.