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Treatments such as TNFinhibitors might have a beneficial effect on cardiovascular risk.
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TNFinhibitors are most cost-effective when used as last active therapy.
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The ICERs for sequential use are of the same order as using the TNFinhibitor alone.
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TNFinhibitors are most cost-effective when used last.
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The next most cost-effective use of TNFinhibitors is third line, as recommended in the 2002 NICE guidance.
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BRAM incorporates improvements in quality of life and mortality, but assumes no effect of TNFinhibitors on joint replacement.
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The study looked at 300 patients who had previously not responded to treatment with a TNFinhibitor, Roche said in a statement.
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TNFinhibitors can have side effects like an increased risk of infection, and other psoriasis drugs may affect the liver or kidneys.
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This study examined the effects of the administration of a TNFinhibitor immediately after myocardial infarction on the development of heart failure.
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The impact of a combined therapy (a TNFinhibitor plus an NSAID) on radiographic spinal progression in AS is unclear.
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The trials tested the drug in patients who were not responding adequately to two commonly prescribed arthritis treatments, TNFinhibitors and methotrexate.
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On top of progress with TNFinhibitors, which can have serious side effects, drugmakers have also found ways to target RA in completely new ways.
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PMID: 23036238 RESULTS: A total of 694 patients with AS on TNFinhibitors in 2007 were identified for data analysis.
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In … RESULTS: A total of 694 patients with AS on TNFinhibitors in 2007 were identified for data analysis.