Knots are some of the most remarkable topologicalfeatures in nature.
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Additionally, the myelination covariance network shared common topologicalfeatures of human brain networks such as small-worldness.
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Particularly, Protein-Protein Interaction (PPI) networks have been used to prioritize genes related to complex diseases according to its topologicalfeatures.
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In this study, we applied persistent homology, an emerging method to analyze topologicalfeatures in a data set, to reveal protein-folding dynamics.
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The availability of human genome-wide protein-protein interactions (PPIs) provides us with new opportunity for discovering hereditary disease-genes by topologicalfeatures in PPIs network.
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This concerted activity of the Sgs1-Top3-Rmi1-RPA represents an important mechanism for disentangling structures resulting from the topologicalfeatures of duplex DNA.