A base containing nitrogen that is found in RNA (but not in DNA) and derived from pyrimidine; pairs with adenine.
1 Thus, cytosine - to- uracil editing may contribute to the sequence diversification of many viruses.
2 Background: Nine novel uracil analogues were synthesized and evaluated as inhibitors of HIV-1.
3 The thymine - uracil exchange constitutes one of the major chemical differences between DNA and RNA.
4 There are two ways for uracil to appear in DNA: thymine replacement and cytosine deamination.
5 Cell-based studies link APOBEC3B activity and subsequent uracil processing to sensitivity to cisplatin and carboplatin.
6 The dUTPase binding pocket is highly specific for uracil .
7 First of all this method was tested on uracil .
8 Decoding of inosine as adenosine and uracil is context-dependent.
9 From the rotational constants of the isotopic species detected, a structure of uracil has been determined.
10 First, a DNA substrate containing uracil base is designed to be conjugated to the magnetic beads.
11 Incorporation of uracil during DNA synthesis is among the most common types of endogenously generated DNA damage.
12 The investigation on the uracil 5-position demonstrates the importance of this RNA modification at the atomic level.
13 Results: Deficiency in UNG uracil - DNA glycosylase alone is sufficient to distort the pathway of hypermutation in mice.
14 DPD could be expressed in significant quantities only when uracil was added to the bacterial growth medium.
15 Besides theoretical investigation, experimental detection of uracil and thymine tautomers was performed by means of steady-state fluorescence.
16 The quadrupole structure originated by the two 14N nuclei of uracil has been completely resolved and assigned.
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