Because of a squamous cell carcinoma that had developed in the venousulcer, one patient in the SEPS group underwent a below-knee amputation.
2
Background: Chronic venous insufficiency, in its final stage can cause venousulcers.
3
There is evidence that compressive therapy favours the healing process of venousulcers.
4
Failure to reepithelialize is the major clinical problem in venousulcers.
5
Local Treating chronic venousulcers has 2 components: topically healing the ulcer and controlling the venous insufficiency.
6
Surgical treatment of venousulcers is based on correcting venous hypertension, by treating incompetent superficial, deep, and perforating veins.
7
In venousulcers, the papillary dermis and the ulcer bed contained convoluted capillaries with phosphotungstic acid haematoxylin-positive pericapillary fibrin cuffs.
8
Seventy patients with 90 venousulcers were randomly assigned to hydrocolloid or conventional dressing and compression therapy at four study centers.
9
These observations suggest that growth factors critical in wound healing, such as TGF-beta, are present within venousulcers, but are abnormally distributed.
10
The combination of four-layer compression with the SCD System on healing venousulcers needs to be tested by a clinical effectiveness study.
11
The study will include 216 individuals (108 per branch) with venousulcers treated in primary care nursing consultations.
12
Venousulcers have a prevalence of 0.5 % to 0.8 % in the general population, and increases starting at 60 years of age.