In total, 3060 VLE frames were analyzed via the CAD multiframe analysis.
2
Multiframe VLE image analysis shows improved BE neoplasia detection compared to single-frame analysis.
3
Those VLEs are primarily being used to offer learning support online rather than offline.
4
Prospectively collected ex-vivo VLE images from 29 BE-patients with and without early neoplasia were retrospectively analyzed.
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Therefore, algorithms that can accurately find cancerous regions are very valuable for the interpretation of VLE data.
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Furthermore, we train and validate our algorithm on a new histopathologically validated set of in-vivo VLE snapshots.
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In total, 3060 VLE frames were automatically extracted and analyzed by CAD in 3.9 seconds.
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However, interpretation of VLE scans is difficult for medical doctors due to both the size and subtlety of the gray-scale data.
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Conclusion: The use of a new VLE-DA showed enhanced diagnostic performance for detecting BE dysplasia ex vivo compared with the current OCT-SI.
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Multiple neighboring VLE frames, corresponding to 1.25 millimeter proximal and distal to each region of interest, were evaluated.
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CAD with multiframe analysis allows for fast and accurate VLE interpretation, thereby showing feasibility of automatic full scan assessment in a real-time setting during endoscopy.