Therefore, cilostazol may produce the relaxation of intact vascular smooth muscle by its inhibition of cyclic adenosinemonophosphate hydrolysis.
2
We found that Dp-3-g reduced phosphorylation of adenosinemonophosphate-activated protein kinase, which may contribute to the observed inhibitory effects on platelet activation.
3
Cyclic adenosinemonophosphate (cAMP) is a major second messenger that triggers various downstream cellular machinery in a wide variety of cells.
4
There is evidence that activation of adenosinemonophosphate-activated protein kinase and endothelial nitric oxide synthase, and a reduced collagen expression are crucial for this effect.
5
Cyclic adenosinemonophosphate stimulates TM expression in cultured SMC, but not EC, while tumor necrosis factor suppresses TM expression in EC but not cultured SMC.
6
Cystic fibrosis results from defects in the gene encoding a cyclic adenosinemonophosphate-dependent chloride ion channel known as the cystic fibrosis transmembrane conductance regulator (CFTR).